导师信息#西南大学药学院研究生导师介绍#陈怡

615877

博士，副教授，硕士研究生导师
出生年月咨询QQ、微信：2544906”体外模型内神经元氧糖剥夺损伤的分子机制研究，主研
8. 国家自然科学基金（NSFC-81473549），基于“EPO是肾精的物质之一”假说和“脑神经血管单元体外模型”的补肾益精健脑机制研究，主研
9. 国家科技部重大新药创制专项（2014ZX09304-306-04），欣梦颗粒的研究开发，主研
10. 教育部博士学科点专项基金（博导类）（20110182110012），"脑神经血管单元"体外模型构建及补肾健脑药效物质筛选，主研
11. 科技部973计划项目子课题（2010CB530604），基于文献及临床经验挖掘的中医方药剂量理论研究，主研
12. 科技部“重大新药创制”孵化基地(重庆)专项（2010ZX09401-306-3-16），抗子宫内膜异位症中药候选新药“内异消缓释胶囊”的研究，主研
代表论文
1、Yi Chen, Dongke Yu, Caixia Zhang, et.al. Lidamycin inhibits tumor initiating cells of hepatocellular carcinoma Huh7 through GSK3β/β-catenin pathway. Molecular Carcinogenesis. 2015, 54(1): pp 1-8
2、Yi Chen, Dongke Yu, Hao Zhang, et.al. CD133+EpCAM+ Phenotype Possesses More Characteristics of Tumor Initiating Cells in Hepatocellular Carcinoma Huh7 Cells. Int J Biol Sci. 2012, 8(7): pp 992-1004
3、陈怡, 邵荣光. 肝癌肝细胞的分子标记与靶向治疗. 中国医药生物技术. 2011, 6(1): 40-43
4、陈怡,徐晓玉,叶兰,祝慧凤,陈红,陈刚.三棱丸抑制大鼠子宫内膜异位症血管生成及VEGF,TNF-ɑ表达的研究 中国中药杂志[J].2008,33（3）:305～307
6、Yang Liu, Qiang Xue, Xu Li, Jifen Zhang, Zhifeng Fu, Binbin Feng, Yi Chen, Xiaoyu Xu. Amelioration of stroke-induced neurological deficiency by lyophilized powder of catapol and puerarin. Int J Biol Sci. 2014, 10(4): pp448-456
7、Yang Liu, Qiang Xue, Qing Tang, Min Hou, Hongyi Qi, Gang Chen, Weihai Chen, Jifen Zhang, Yi Chen, Xiaoyu Xu. A simple method for isolating and culturing the rat brain microvascular endothelial cells. Microvascular Research. 2013, Vol 90: pp199-205
8、Qing Tang, Fanghong Shang, Xiaocui Wang, Yang Yang, Gang Chen, Yi Chen, Jifen Zhang, Xiaoyu Xu. Combination use of ferulic acid, ligustrazine and tetrahydropalmatine inhibits the growth of ectopic endometrial tissue: A multi-target therapy for endometriosis rats. Journal of Ethnopharmacology. 2014, 151( 3): pp1218-1225
9、Caixia Zhang, Hongwei He, Hao Zhang, Dongke Yu, Wuli Zhao, Yi Chen, Rongguang Shao. The blockage of Ras/ERK pathway augments the sensitivity of SphK1 inhibitor SKI II in human hepatoma HepG2 cells. Biochemical and Biophysical Research Communications. 2013, 434(1): pp35-41
10、WuLi Zhao, HongWei He, KaiHuan Ren, Hao Zhang, Yi Chen, RongGuang Shao. Myofibrillogenesis regulator-1 promotes cell adhesion and migration in human hepatoma cells. Chinese Science Bulletin. 2013, 58(24): pp3007-3014