导师信息#江南大学生物工程学院硕士生导师介绍#蔡宇杰

18751976918

性别：男出生年月：1973.12职称、职务：教授电话：0510-85327725电子邮箱：yjcai@jiangnan.edu.cn【研究领域】
主要从事生物化学及下游工程等方面交叉学科的研究。主要研发天然功能性产物：竹红菌素、虫草素、EPA、DHA、ARA及功能性酶等。已产业化产品：模拟移动床色谱、工业制备色谱系统【科研项目】
主持项目：集成化通用型智能模拟移动床色谱装置开发与产业化,江苏省科技攻关重点项目,2006.4-2007.12生物、医药用模拟移动床色谱分离纯化装置关键技术开发及产业化,江苏省科技成果转化重大专项项目，BA2007077,2007.10-2010.9竹黄菌全细胞催化合成竹红菌素关键技术研究,科技部科技人员服务企业项目，2009GJ10038,2009.5-2010.5,基于蛋白质组差异分析方法的竹红菌素代谢途径关键催化过程研究，国家自然科学基金，21045007，2011.1-2011.12,广谱抗癌新药竹红菌素全细胞合成及纯化关键技术研究,江苏省科技创新与成果转化（重大科技支撑与自主创新）专项引导资金BY2010117,2010.7-2012.12中央高校基本科研业务费专项资金资助JUSRP21120，2011.1-2012.12竹红菌素合成代谢过程中关键酶快速分析平台的构建及应用研究，国家自然科学基金，21275066,2013.1-2016.12参与项目：降血压活性肽的基因表达和分离技术的研究(863探索导向类)科技部2007.10-2010.9【科研成果及奖励】2008年中国石油与化学工业联合会科技进步三等奖（排名第一）2012年中国石油与化学工业联合会科技进步一等奖（排名第一）2012年教育部科技进步二等奖（排名第一）2012年江苏省科技进步三等奖（排名第三）【主要论著】YangY,DingY,LiaoX,CaiY:PurificationandcharacterizationofanewlaccasefromShiraiasp.SUPER-H168.ProcessBiochem2013,48(2):351-357.LiuJ,CaiY,LiaoX,HuangQ,HaoZ,HuM,ZhangD,LiZ:Efficiencyoflaccaseproductionina65-Lair-liftreactorforpotentialgreenindustrialandenvironmentalapplication.In:JournalofCleanerProduction.vol.39;2013:154-160.LiuJ,CaiY,LiaoX,HuangQ,HaoZ,HuM,ZhangD:PurificationandCharacterisationofaNovelThermalStableLaccasefromPycnoporusSp.Sybc-L3anditsuseinDyeDecolorisation.Biology&Environment:ProceedingsoftheRoyalIrishAcademy2013,113(1):1-13.DingY,CaiY:ConformationaldynamicsofxylanaseafromStreptomyceslividans:ImplicationsforTIM-barrelenzymethermostability.Biopolymers2013,99(9):594-604.ZengX,CaiY,LiaoX,ZengX,LuoS,ZhangD:AnthraquinonedyeassistedthedecolorizationofazodyesbyanovelTrametestrogiilaccase.ProcessBiochem2012,47(1):160-163.LiuJ,CaiY,LiaoX,HuangQ,HaoZ,HuM,ZhangD:SimultaneouslaccaseproductionandcolorremovalbyculturingfungusPycnoporussp.SYBC-L3inatextilewastewatereffluentsupplementedwithalignocellulosicwastePhragmitesaustralis.BullEnvironContamToxicol2012,89(2):269-273.HuMM,CaiYJ,LiaoXR,HaoZK,LiuJY:DevelopmentofanHPLCmethodtoanalyzeandprepareelsinochromeCandhypocrellinAinthesubmergedfermentationbrothofShiriasp.SUPER-H168.BiomedChromatogr2012,26(6):737-742.HaoZ,CaiY,LiaoX,ZhangX,FangZ,ZhangD:OptimizationofnutritionfactorsonchitinaseproductionfromanewlyisolatedChitiolyticbactermeiyuanensisSYBC-H1.BrazJMicrobiol2012,43:177-186.DingY,CaiY,HanY,ZhaoB,ZhuL:Applicationofprincipalcomponentanalysistodeterminethekeystructuralfeaturescontributingtoironsuperoxidedismutasethermostability.Biopolymers2012,97(11):864-872.DingY,CaiY,HanY,ZhaoB:Comparisonofthestructuralbasisforthermalstabilitybetweenarchaealandbacterialproteins.Extremophiles2012,16(1):67-78.ZengXK,CaiYJ,LiaoXR,LiW,ZhangDB:DecolorizationofsyntheticdyesbycrudelaccasefromanewlyisolatedTrametestrogiistraincultivatedonsolidagro-industrialresidue.JHazardMater2011,187(1-3):517-525.ZengHW,CaiYJ,LiaoXR,ZhangF,ZhangDB:AninducedstrategyofregulationofcarbonmetabolismandstatisticaloptimizationforproductionenhancementofcatalasebySerratiamarcescensSYBC08fromsludgewithhydrogenperoxide.AsianJournalofChemistry2011,23(4):1488-1492.ZengHW,CaiYJ,LiaoXR,ZhangF,ZhangDB:Production,characterization,cloningandsequenceanalysisofamonofunctionalcatalasefromSerratiamarcescensSYBC08.JBasicMicrobiol2011,51(2):205-214.SuYJ,SunJ,RaoS,CaiYJ,YangYJ:PhotodynamicantimicrobialactivityofhypocrellinA.JPhotochemPhotobiolB2011,103(1):29-34.SuY,SiS,QiaoL,CaiY,XuZ,YangY:TheeffectofahypocrellinAenricheddietoneggyolkqualityandhypocrellinAdistributionsinthemeatoflayinghens.EurFoodResTechnol2011,232(6):935-940.LiGY,CaiYJ,LiaoXR,YinJ:Anovelnonionicsurfactant-andsolvent-stablealkalineserineproteasefromSerratiasp.SYBCHwithduckweedasnitrogensource:production,purification,characteristicsandapplication.JIndMicrobiolBiotechnol2011,38(7):845-853.LiGY,CaiYJ,LiaoXR,YinJ:Enzymaticsynthesisofsucroseoctbbcetateusinganovelalkalineprotease.BiotechnolLett2011,33(3):607-610.HaoZK,CaiYJ,LiaoXR,LiangXH,LiuJ,FangZ,HuMM,ZhangDB:ChitinolyticbactermeiyuanensisSYBC-H1(T),Gen.Nov.,sp.Nov.,aChitin-DegradingBacteriumIsolatedFromSoil.CurrMicrobiol2011,62(6):1732-1738.CaiYJ,LiaoXR,LiangXH,DingYR,SunJ,ZhangDB:InductionofhypocrellinproductionbyTritonX-100undersubmergedfermentationwithShiraiasp.SUPER-H168.NBiotechnol2011,28(6):588-592.CaiY,LiuS,LiaoX,DingY,SunJ,ZhangD:PurificationandpartialcharacterizationofantifreezeproteinsfromleavesofLigustrumlucidumAit.FoodandBioproductsProcessing2011,89(2):98-102.ZengHW,CaiYJ,LiaoXR,QianSL,ZhangF,ZhangDB:Optimizationofcatalaseproductionandpurificationandcharacterizationofanovelcold-adaptedCat-2frommesophilicbacteriumSerratiamarcescensSYBC-01.AnnMicrobiol2010,60(4):701-708.YuanBH,CaiYJ,LiaoXR,YunLH,ZhangF,ZhangDB:Isolationandidentificationofacold-adaptedlipaseproducingstrainfromdecayedseedsofGinkgobilobaL.andcharacterizationofthelipase.AfrJBiotechnol2010,9(18):2661-2667.WangZX,CaiYJ,LiaoXR,ZhangF,ZhangD,LiZL:ProductionandCharacterizationofaNovelLaccasewithColdAdaptationandHighThermalStabilityfromanIsolatedFungus.ApplBiochemBiotechnol2010,162(1):280-294.WangZX,CaiYJ,LiaoXR,TaoGJ,LiYY,ZhangF,ZhangDB:PurificationandcharacterizationoftwothermostablelaccaseswithhighcoldadaptedcharacteristicsfromPycnoporusspSYBC-L1.ProcessBiochem2010,45(10):1720-1729.SunJ,ZhaoJ,WuXJ,FangW,CaiYJ,XuWB:ParameterestimationforchaoticsystemswithaDriftParticleSwarmOptimizationmethod.PhysicsLettersA2010,374(28):2816-2822.SuYJ,RaoSQ,CaiYJ,YangYJ:PreparationandcharacterizationoftheinclusioncomplexofhypocrellinAwithhydroxypropyl-beta-cyclodextrin.EurFoodResTechnol2010,231(5):781-788.CaiYJ,WuHG,LiaoXR,DingYR,SunJ,ZhangDB:PurificationandCharacterizationofNovelManganesePeroxidasefromRhizoctoniasp.SYBC-M3.BiotechnolBioprocessEng2010,15(6):1016-1021.CaiYJ,WeiZY,LiaoXR,DingYR,SunJ:CharacterizationofthreeextracellularpolysaccharidesfromShiraiaspSuper-H168undersubmergedfermentation.CarbohydrPolym2010,82(1):34-38.CaiYJ,LiangXH,LiaoXR,DingYR,SunJ,LiXH:High-YieldHypocrellinAProductioninSolid-StateFermentationbyShiraiaspSUPER-H168.ApplBiochemBiotechnol2010,160(8):2275-2286.CaiY,SunJ,WangJ,DingY,LiaoX,XuW:QPSOBT:Onecodonusageoptimizationsoftwareforproteinheterologousexpression.JournalofBioinformaticsandSequenceAnalysis2010,2(2):25-29.SuYJ,YinXY,RaoSQ,CaiYJ,ReuhsB,YangYJ:NaturalcolourantfromShiraiabambusicola:stabilityandantimicrobialactivityofhypocrellinextract.InternationalJournalofFoodScienceandTechnology2009,44(12):2531-2537.32.LiangXH,CaiYJ,LiaoXR,WuK,WangL,ZhangDB,MengQ:IsolationandidentificationofanewhypocrellinA-producingstrainShiraiaspSUPER-H168.MicrobiolRes2009,164(1):9-17.33.DingDW,DingYR,LiLN,CaiYJ,XuWB:Structuralandfunctionalanalysisofgiantstrongcomponentofbacillusthuringiensismetabolicnetwork.BrazJMicrobiol2009,40(2):411-416.34.CaiYJ,WangL,LiaoXR,DingYR,SunJ:Purificationandpartialcharacterizationoftwonewcold-adaptedlipasesfrommesophilicGeotrichumsp.SYBCWU-3.ProcessBiochem2009,44(7):786-790.35.DingDW,DingYR,LuKZ,ChenSW,CaiYJ,XuWB:RobustnessinB-thuringiensisMetabolicNetwork.RivistaDiBiologia-BiologyForum2008,101(2):265-277.36.DingDW,DingYR,CaiYJ,ChenSW,XuWB:Exploringpoly-beta-hydroxybutyratemetabolismthroughnetwork-basedextremepathwayanalysis.RivistaDiBiologia-BiologyForum2008,101(1):67-79.37.CaiYJ,SunJ,WangJ,DingYR,TianN,LiaoXR,XuWB:OptimizingthecodonusageofsyntheticgenewithQPSOalgorithm.JTheorBiol2008,254(1):123-127.38.CaiYJ,DingYR,TaoGJ,LiaoXR:Productionof1,5-dihydroxy-3-methoxy-7-methylanthracene-9,10-dionebysubmergedcultureofShiraiabambusicola.JMicrobiolBiotechnol2008,18(2):322-327.39.DingYR,CaiYJ,ZhangGX,XuWB:Theinfluenceofdipeptidecompositiononproteinthermostability.FEBSLett2004,569(1-3):284-288.